Research
Gosha-jinki-gan for Bladder Health: Evidence, Interactions and Cautions
Gosha-jinki-gan is an ingredient used in bladder supplements marketed to women. Below is what it has actually been studied for, how strong that evidence is, the drug interactions and cautions on record, and the primary source our grade rests on — all drawn from the HerWellReport ingredient dataset.
Also sold as: Goshajinkigan; GJG; niu che shen qi wan; a ten-herb Japanese kampo formula
What the evidence says about Gosha-jinki-gan
The bladder evidence is small, almost entirely Japanese and largely uncontrolled: a representative example is a prospective observational study of 56 women taking gosha-jinki-gan for four weeks, in which the overactive bladder symptom score fell from 7.57 to 6.73, with the gain concentrated in the 36 women who were sensitive to cold. With no placebo group, that change cannot be attributed to the formula. When gosha-jinki-gan was tested against placebo in a large double-blind phase III trial (GENIUS, 182 patients, a different indication), it not only failed but was stopped early because neuropathy was worse in the treated group, which is a fair warning against assuming a kampo formula is inert.
The grade "very limited" means: very limited — Mostly animal, laboratory or anecdotal evidence, with at most a single weak human study. Grades are explained in full on our methodology page.
Read the primary source this grade rests on (opens in a new tab).
Gosha-jinki-gan drug interactions
No documented drug interactions in the sources we checked. That is not the same as proof of safety alongside your medication — it usually means the question has not been studied. Ask a pharmacist before combining it with prescription drugs.
Who should be careful with Gosha-jinki-gan
- Contains processed aconite root, so treat it as a medicine rather than a food supplement and take it under professional supervision
Read more on HerWellReport
This entry is generated from row "Gosha-jinki-gan" of the HerWellReport ingredient dataset (v2.1, updated 2026-09-23). The dataset is free to reuse under CC BY 4.0 — how to cite it. Ingredient evidence is not evidence for any finished product, and nothing here is medical advice.