Research
Pumpkin seed extract for Bladder Health: Evidence, Interactions and Cautions
Pumpkin seed extract is an ingredient used in bladder supplements marketed to women. Below is what it has actually been studied for, how strong that evidence is, the drug interactions and cautions on record, and the primary source our grade rests on — all drawn from the HerWellReport ingredient dataset.
Also sold as: Cucurbita pepo
What the evidence says about Pumpkin seed extract
Small clinical studies report improvements in urgency and night trips. The studies are small, often short and frequently industry-connected - a promising direction rather than settled science. The trial most often cited for this ingredient tested a pumpkin seed plus soy germ combination in 120 women over 12 weeks (2014); it was funded by the ingredient supplier, tested the combination rather than pumpkin seed alone, and is not indexed in PubMed. The PubMed-indexed study of pumpkin seed oil is weaker still: 45 subjects, no placebo group, 10 g of oil a day, with a co-author employed by the company that produced the oil.
The grade "limited" means: limited — One or two small human trials, or trials for a closely related outcome. Grades are explained in full on our methodology page.
Read the primary source this grade rests on (opens in a new tab).
Pumpkin seed extract drug interactions
No documented drug interactions in the sources we checked. That is not the same as proof of safety alongside your medication — it usually means the question has not been studied. Ask a pharmacist before combining it with prescription drugs.
Who should be careful with Pumpkin seed extract
No specific cautions recorded beyond the usual ones for any supplement: check with your doctor if you are pregnant, breastfeeding, have liver or kidney disease, or take regular medication.
Read more on HerWellReport
- Best Bladder Control Supplements for Women (2026): What’s Actually in Them
- Swanson Go-Less Bladder Control Review: What’s Actually in It, and How the Dose Compares to AZO
- FemiCore vs AZO Bladder Control: Ingredients, Price and Guarantee Compared
- Do Bladder Control Supplements Actually Work? What the Evidence Says for Women Over 40
- Bladder Supplement Side Effects and Drug Interactions: The Full List
This entry is generated from row "Pumpkin seed extract" of the HerWellReport ingredient dataset (v2.1, updated 2026-09-23). The dataset is free to reuse under CC BY 4.0 — how to cite it. Ingredient evidence is not evidence for any finished product, and nothing here is medical advice.