Research
Urox (Crataeva nurvala, horsetail and Lindera aggregata)
Urox is a fixed three-herb blend used in bladder supplements marketed to women, and one of the few branded blends in this category with a randomised trial behind it. Below is what it has actually been studied for, how strong that evidence is, the cautions on record, and the primary source our grade rests on — all drawn from the HerWellReport ingredient dataset.
Also sold as: Cratevox; Crataeva nurvala stem bark; horsetail stem; Lindera aggregata root; sold as Urox or Bedtime Buddy
What the evidence says about Urox
The only branded blend in this category with a properly designed trial behind it. A phase 2 randomised, double-blind, placebo-controlled trial in 150 adults (59 per cent women, average age 63) reported significantly lower daytime frequency, fewer night-time trips, less urgency and less incontinence after 8 weeks, with no side effects causing withdrawal. Three things temper it: one of the authors is from Seipel Group, the company that makes Urox; it is a single phase 2 trial at two primary care centres, not an independent replication; and the participants were a mixed group of men and women with overactive bladder, so it says nothing about stress leaks specifically. Graded limited rather than moderate for that reason. A separate trial of the same blend in children with bedwetting is registered but is a protocol, not a result.
The grade "limited" means: limited — One or two small human trials, or trials for a closely related outcome. Grades are explained in full on our methodology page.
Read the primary source this grade rests on (opens in a new tab).
Urox drug interactions
- No documented interactions found in the sources we checked
Who should be careful with Urox
- Horsetail is a diuretic and the European Medicines Agency registered it on traditional use only
- see the separate horsetail row. Not studied in pregnancy or breastfeeding
Read more on HerWellReport
- Best Bladder Control Supplements for Women (2026): What’s Actually in Them
- Urox Bladder Control Review (2026): The Trial Behind It, and the Hidden Dose
- Confitrol24 Review (2026): The Trial Is Real, But the Label Doesn’t Say How Much
- Swanson Go-Less Bladder Control Review: What’s Actually in It, and How the Dose Compares to AZO
- Cystex Review (2026): The Cranberry Dose It Won’t Disclose
This entry is generated from row "Urox (Crataeva nurvala + Equisetum arvense + Lindera aggregata)" of the HerWellReport ingredient dataset (v2.1, updated 2026-09-23). The dataset is free to reuse under CC BY 4.0 — how to cite it. Ingredient evidence is not evidence for any finished product, and nothing here is medical advice.